Signal transduction by reactive oxygen species

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Signal transduction by reactive oxygen species

Although historically viewed as purely harmful, recent evidence suggests that reactive oxygen species (ROS) function as important physiological regulators of intracellular signaling pathways. The specific effects of ROS are modulated in large part through the covalent modification of specific cysteine residues found within redox-sensitive target proteins. Oxidation of these specific and reactiv...

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Reactive Oxygen Species: Friends and Foes of Signal Transduction

1Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043 Orbassano, Italy 2Department of Biochemical Sciences, University of Florence, viale Morgagni 50, 50134 Florence, Italy 3Department of Biotechnology, University of Siena, Via Fiorentina 1, 53100 Siena, Italy 4Department of Experimental and Diagnostic Medicine, University of Ferrara, Via Borsari 46, 44...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2011

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.201102095